Prediction of the Potency of Mammalian Cyclooxygenase Inhibitors with Ensemble Proteochemometric Modelling 

Get Complete Project Material File(s) Now! » Synergy between ligand and target space An analysis of the drug-target interaction network demonstrated that a given ligand interacts with six protein targets on average at therapeutic concentrations [Mestres et al. (2009)]. Targets...

Hybrid approaches using Mutual Information Tests

Get Complete Project Material File(s) Now! » Interpretation of a DAG The set of conditional independence relationships among the variables V, en-tailed by a DAG G, can be deduced by applying a graphical criterion called the d-separation [Pearl, 2000] (see...

Microstructure evolution during PIA tests

Get Complete Project Material File(s) Now! » Fission gases The set of stable gases created in PWR is of the order of 0.31 at/fission. As can be seen from Table 1.1, the gases thus formed, especially Xenon, rep-resent significant amounts....

Estimation of electron temperature at sub-spin time resolution

Get Complete Project Material File(s) Now! » Electron Measurements The two instruments aboard Cluster that measure the properties of the electrons are PEACE and RAPID. PEACE consists of two top-hat electrostatic analyzers (shown in gure 3.8) that measure 3-dimensional electron...

Split-and-Merge Port-centric Network Anomaly Detection

Get Complete Project Material File(s) Now! »  Statistical and machine learning techniques Statistical and machine learning (ML) techniques can be leveraged for complex problems arising in network operation and management [11]. Last years have witnessed a surge of such tech-niques,...

Deterministic solutions of the haploid model for neutral subfunctionalization 

Get Complete Project Material File(s) Now! » Evolution through WGD and SSD Di erent mechanisms can result in the duplication of regions of the genome, ranging from an individual gene to the entire genome. In particular, a special attention will...

Toxoplasma gondii antigen for MAT produced in cell culture

Get Complete Project Material File(s) Now! » Meat protection and inactivation of T. gondii in meat products In 1965 prevalence of French population was 83%; 43.8% - 2003; and 37% in 2010 (constantly decreasing). The prevalence always varied substantially according...

Mechanisms of the IgA immune response in the gut 

Get Complete Project Material File(s) Now! » Log-likelihood maximization principle The log-likelihood maximization principle [46] allows to get the best tting parameters that t a data set with an assumed probability distribution function. Let us suppose we have at our...

Natural Killer (NK) cells and other innate lymphoid cells(?)

Get Complete Project Material File(s) Now! » Hepatic stem cells Hepatic stem cells have been hypothesized to exist in the liver, taking part in its regeneration after injury. In rat, “oval cells” were observed in injury where hepatocytes did not...

New inverter-based SC integrator model with parasitic capacitors

Get Complete Project Material File(s) Now! » From CMOS Image Sensor to Column-parallel ADC The first devices with CMOS image sensor (CIS) technology on the market for the public use raised in 1990s. Despite of its low image quality in...