How inhibition shapes cortical information processing: functional importance of PV and SOM interneurons

Get Complete Project Material File(s) Now! » Novels methods for investigating the functional connec-tivity The major aim of systems neuroscience is to understand how the brain processes information, encodes perception and generates behavior. These operations are determined by the structure...

Levitation of micro-particles in a Paul trap

Get Complete Project Material File(s) Now! » Nuclear Mangetic Resonance Rabi’s discovery was followed by its implementation in a solid state system: Bloch ex-plained [85] and observed -simultaneously with Purcell- that this precession induced in solid could be observed macroscopically....

Universality of phase transitions in noiseless linear regression 

Get Complete Project Material File(s) Now! » The replica method for spin glass models Introduction to spin glass models Spin glass models were originally introduced to describe some metal alloys such as copper-magnesium or gold-iron. They differ from standard ferromagnets...

Structural Characterization of the GB virus B Envelope Glycoprotein.E2

Get Complete Project Material File(s) Now! » Therapeutic potential of neutralizing antibodies Despite the recent advances in HCV treatment, vaccination would still represent the best way to reduce the global burden of HCV. However, to date no licensed vaccine exists...

The Tumor Suppressor Smad4/DPC4 is Regulated by Phosphorylations that Integrate FGF, Wnt and TGF-beta Signaling

Get Complete Project Material File(s) Now! » Dorsal–ventral patterning: a morphogenetic gradient of BMP ligands The earliest requirement for BMP signaling in an embryo is during the patterning of cell fates along its D–V axis. Formation of a D–V gradient...

Cell penetrating peptide as cell delivery vectors

Get Complete Project Material File(s) Now! » Antibacterial and antifungal activity The Schiff base formed from pyridine-2-carboxaldehyde SMDTC and its Zn complex showed marked and broad antimicrobial and antifungal activities compared to the S-benzyl derivatives with MIC values as low...

Avian influenza in Vietnam: associating classic models to create a world model 

Get Complete Project Material File(s) Now! » Representing earthworms actions on soil A fit example of approach shift is given by the Sworm model [Mar08, Bla09]. The question at the origin of this work is the understanding of the earthworms...

Mutation of a single amino-acid on ribosomal protein uL11 generates a Minute-like phenotype in Drosophila

Get Complete Project Material File(s) Now! » Ribosome biogenesis drives cellular organization The nucleolus is a membrane-less organelle, thought to form upon coalescence of ribosome biogenesis factors around the site of rDNA transcription. It has thus been described as an...

Directed evolution of protein tags binding and activating far-red-emitting fluorogens 

Get Complete Project Material File(s) Now! » Biarsenical- tetracysteine tagging system The first tag developed for site-specific protein labeling was the tetracysteine motif, a short peptide usually composed of six amino acids CCPGCC that can bind with biarsenical dyes.36 The...

Collective motion of bacteria in a temperature gradient

Get Complete Project Material File(s) Now! » Trade-ošs in adaptation to high temperature Bennett and Lenski (ÕÉÉì) reports no signicant trade-oš in temperature of adaptation aŸer 2000 generations (Fig. Õ.ß): increase in relative tness is signicant at adaptation temperature but...